Orthopaedic Nurses Certification Board (ONCB) Metabolic/Inflammatory/Tumors Practice Exam

Disable ads (and more) with a membership for a one time $2.99 payment

Get prepared for the Orthopaedic Nurses Certification Board Exam. Study with multiple choice questions for metabolic, inflammatory, and tumor conditions in orthopaedics. Each question is crafted to enhance your understanding and readiness!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

Practice this question and more.

Which medication is known to potentially contribute to the development of gout?

Atenolol (Tenormin®)
Esomeprazole (Nexium®)
Metformin (Glucophage®)
Hydrochlorothiazide (HCTZ)

The correct answer is: Hydrochlorothiazide (HCTZ)

Hydrochlorothiazide (HCTZ) is recognized for its association with the development of gout due to its diuretic properties. Diuretics can lead to dehydration and increase uric acid levels in the blood by promoting its reabsorption in the kidneys. Elevated uric acid levels can result in the crystallization of uric acid in the joints, which is the underlying cause of gout attacks. In contrast, atenolol, esomeprazole, and metformin do not have a significant impact on uric acid metabolism. Atenolol, as a beta-blocker, may have minor effects on the body that do not notably influence gout development. Esomeprazole, a proton pump inhibitor, is primarily used to reduce gastric acid production and is not associated with uric acid levels. Metformin is an antidiabetic medication that generally has a neutral or possibly beneficial effect on uric acid levels. Therefore, hydrochlorothiazide stands out as the medication most likely to contribute to the onset of gout.