Orthopaedic Nurses Certification Board (ONCB) Metabolic/Inflammatory/Tumors Practice Exam

Paget's disease is primarily confirmed through radiological findings, which play a critical role in the diagnosis of this condition. Radiological imaging, particularly X-rays, can reveal distinctive changes in the affected bones, such as thickening or enlargement, which are hallmark signs of Paget's disease. These imaging studies enable healthcare professionals to visualize the patterns of bone remodeling and determine the extent of the disease. While urine and blood testing can provide supportive information, such as elevated alkaline phosphatase levels in blood tests or abnormalities in urine markers due to increased bone turnover, these tests are not definitive for diagnosing Paget's disease. Similarly, although MRI can be helpful in assessing the structural changes and complications associated with Paget's disease, it is not the primary method for confirmation. Thus, radiological findings remain the cornerstone of diagnosing this condition.